There’s a lot of things that would have influence to what ur taking about man.

From what I can think of theres

1. Genetics
2. equipment 
3. skill
4. environment
5. medium

I can’t think of anything else right off but maybe someone else will chime in.

So i can assume youve had successful grows using fem photoperiod plants?  for a decent grower, 2 ounces per plant should not be hard to get from 4 plants. So a half pound is not a problem. Try not to put the cart before the horse if you know what i mean.

what strain do you plan to grow? what is your growing experience? what kinda lights? what kind of nutrients? soil or hydro?

also welcome to weedportal